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Discover highly impactful charities that use evidence and cost-effectiveness to address the world’s most pressing challenges, saving and improving lives globally.
Maximizing Impact Through Evidence-Based Solutions
The organizations featured in this list focus on interventions that deliver the greatest good for every dollar spent. By addressing critical global challenges — such as improving health and alleviating poverty, advancing animal welfare, and reducing catastrophic risks — they maximize their resources to save and improve lives. Their work spans programs like malaria prevention, deworming, and cash transfers to reduce poverty, alongside efforts to improve animal welfare and address global risks such as pandemics and AI safety — all driven by evidence and cost-effectiveness to maximize impact.
Empowering Change: Supporting Cost-Effective and High-Impact Organizations
We celebrate these organizations for their commitment to rigorous evaluation, cost-effectiveness, and their ability to tackle some of the world’s most pressing problems with measurable success. Their work demonstrates the power of prioritizing interventions that achieve maximum impact while remaining transparent and accountable.
These organizations' missions embody the principles of effective giving and drive meaningful, long-lasting change globally. We invite you to explore and support these organizations by donating through the Charity Navigator Giving Basket.
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View the criteria we use to select charities for our Where to Give Now, Popular Charities, and Best Charities lists.